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Alternative approaches to myeloid suppressor cell therapy in transplantation: comparing regulatory macrophages to tolerogenic DCs and MDSCs

URN to cite this document:
urn:nbn:de:bvb:355-epub-260846
Riquelme, Paloma ; Geissler, Edward K. ; Hutchinson, James A.
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Date of publication of this fulltext: 23 Oct 2012 06:38


Abstract

Several types of myeloid suppressor cell are currently being developed as cell-based immunosuppressive agents. Despite detailed knowledge about the molecular and cellular functions of these cell types, expert opinions differ on how to best implement such therapies in solid organ transplantation. Efforts in our laboratory to develop a cell-based medicinal product for promoting tolerance in renal ...

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