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Alternative approaches to myeloid suppressor cell therapy in transplantation: comparing regulatory macrophages to tolerogenic DCs and MDSCs

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Riquelme, Paloma ; Geissler, Edward K. ; Hutchinson, James A.
License: Creative Commons Attribution 3.0
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Date of publication of this fulltext: 23 Oct 2012 06:38


Several types of myeloid suppressor cell are currently being developed as cell-based immunosuppressive agents. Despite detailed knowledge about the molecular and cellular functions of these cell types, expert opinions differ on how to best implement such therapies in solid organ transplantation. Efforts in our laboratory to develop a cell-based medicinal product for promoting tolerance in renal ...


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