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Skin tissue fluid levels of cefotiam in healthy man following oral cefotiam hexetil

Korting, H. C., Schäfer-Korting, M., Kees, Frieder K., Lukacs, A. and Grobecker, H. (1990) Skin tissue fluid levels of cefotiam in healthy man following oral cefotiam hexetil. European journal of clinical pharmacology 39 (1), pp. 33-36.

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Abstract

Cefotiam hexetil is a pro-drug of cefotiam available for oral administration. To evaluate cefotiam concentrations at the active site in skin and soft-tissue infections, drug levels in skin suction blister fluid (SBF), cantharides blister fluid (CBF) and serum were determined. Six healthy subjects received oral cefotiam 400 mg as cefotiam hexetil. On an other day 200 mg was injected intravenously. ...

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Item type:Article
Date:1990
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Identification Number:
ValueType
2276386PubMed ID
Classification:
NotationType
Administration, OralMESH
AdultMESH
Blister/metabolismMESH
Body Fluids/metabolismMESH
Cefotiam/pharmacologyMESH
Chromatography, High Pressure LiquidMESH
FemaleMESH
HumansMESH
Injections, IntravenousMESH
MaleMESH
Prodrugs/pharmacokineticsMESH
Protein BindingMESH
Random AllocationMESH
Skin/metabolismMESH
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Yes
Item ID:26834
Owner only: item control page

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