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The effects of ocular hypotensive doses of PGF2 alpha-isopropylester on anterior segment morphology

Lütjen-Drecoll, E. ; Tamm, Ernst R.


In cynomolgus monkeys, PGF2 alpha when topically applied in the isopropylester form in doses sufficient to reduce IOP, has much less effect on the ciliary epithelium than PGs have previously been reported to cause in rabbits. We observed no accumulation of wandering cells (leukocytes and histiocytes), which are one of the typical signs of inflammation. The changes noted in the ciliary epithelium ...


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