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Membrane voltage recordings in a cell line derived from human ciliary muscle

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Korbmacher, C. ; Helbig, H. ; Coroneo, M. ; Erickson-Lamy, K. A. ; Stiemer, B. ; Tamm, Ernst R. ; Lütjen-Drecoll, E. ; Wiederholt, M.
Date of publication of this fulltext: 03 Dec 2012 14:25


A smooth muscle cell line (H7CM) was established from the ciliary muscle of a 1-day-old human infant. The cultured cells had a normal female karyotype (46 XX) and could be maintained in cell culture for at least 11 generations. A common feature of confluent cultures was the presence of abundant bundles of 6-7 nm microfilaments associated with dense bodies. Both the ultrastructural appearance and ...


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