Differential effects of extracellular anions on renin secretion from isolated perfused rat kidneys

URN to cite this document:: urn:nbn:de:bvb:355-epub-269199

Scholz, H. ; Götz, K. H. ; Hamann, M. ; Kurtz, Armin

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Date of publication of this fulltext: 04 Dec 2012 13:34

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Abstract

We investigated the relevance of anions for the regulation of renin secretion from the kidneys. For this purpose we measured renin release from isolated rat kidneys that were perfused with medium containing either 120 mmol/l (normal) chloride or 95 mmol/l of isethionate, acetate, or nitrate anions in exchange for equimolar amounts of chloride. Lowering the extracellular chloride concentration by ...