Renal autacoids are involved in the stimulation of renin gene expression by low perfusion pressure

URN to cite this document:: urn:nbn:de:bvb:355-epub-269204
DOI to cite this document:: 10.5283/epub.26920

Schricker, Karin ; Hamann, Marlies ; Kaissling, B. ; Kurtz, Armin

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Date of publication of this fulltext: 05 Dec 2012 10:23

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Abstract

Renal autacoids are involved in the stimulation of renin gene expression by low perfusion pressure. This study aimed to examine the role of local autacoids for the regulation of renin secretion and renin gene expression by the renal perfusion pressure. To this end the effects of unilateral reduction of renal perfusion by 0.2 mm clips on plasma renin activity and on renal renin mRNA levels were ...