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Role of renal nerves for the expression of renin in adult rat kidney

URN to cite this document:
Holmer, S. ; Rinne, B. ; Eckardt, K. U. ; Le Hir, M. ; Schricker, K. ; Kaissling, B. ; Riegger, G. ; Kurtz, Armin
Date of publication of this fulltext: 04 Dec 2012 13:47


Utilizing a combination of mechanical and chemical unilateral denervation, we have examined the relevance of renal innervation for the expression of renin in kidneys of adult rats. Renal denervation led to a reduction by 57 +/- 4% of renin-containing areas in denervated kidneys as quantitated by morphometry of kidney sections immunoreactive against a polyclonal antirenin antibody. Preprorenin ...


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