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Holmer, S. ; Eckardt, Kai-Uwe ; Aedtner, O. ; LeHir, M. ; Schricker, K. ; Hamann, M. ; Götz, Karlheinz ; Riegger, Günter A. J. ; Moll, Waldemar ; Kurtz, Armin

Which factor mediates reno-renal control of renin gene expression?

Holmer, S., Eckardt, Kai-Uwe, Aedtner, O., LeHir, M., Schricker, K., Hamann, M., Götz, Karlheinz, Riegger, Günter A. J., Moll, Waldemar and Kurtz, Armin (1993) Which factor mediates reno-renal control of renin gene expression? Journal of hypertension 11 (10), pp. 1011-1019.

Date of publication of this fulltext: 11 Dec 2012 08:49
Article
DOI to cite this document: 10.5283/epub.26931


Abstract

The results suggest that the suppression of renin gene expression in the contralateral kidneys of stenosed kidneys is not due to compensatory renal growth nor mediated by systemic blood pressure, angiotensin II AT1 receptors or renal nerves. We therefore hypothesize that kidneys with reduced perfusion release a humoral factor that acts as a potent inhibitor of renin gene expression.



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Details

Item typeArticle
Journal or Publication TitleJournal of hypertension
Publisher:Lippincott
Open Access Type:Transfer of rights -1994
Volume:11
Number of Issue or Book Chapter:10
Page Range:pp. 1011-1019
Date1993
InstitutionsBiology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number
ValueType
8258664PubMed ID
Classification
NotationType
Angiotensin Receptor AntagonistsMESH
AnimalsMESH
Biphenyl Compounds/pharmacologyMESH
ConstrictionMESH
DenervationMESH
Gene Expression RegulationMESH
Imidazoles/pharmacologyMESH
Kidney/physiologyMESH
LosartanMESH
MaleMESH
Nervous System Physiological PhenomenaMESH
RNA, Messenger/metabolismMESH
RatsMESH
Rats, Sprague-DawleyMESH
Renal Artery/physiologyMESH
Renal Circulation/physiologyMESH
Renin/geneticsMESH
Tetrazoles/pharmacologyMESH
Dewey Decimal Classification500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgUnknown
URN of the UB Regensburgurn:nbn:de:bvb:355-epub-269317
Item ID26931

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