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Pharmacokinetics of recombinant human erythropoietin applied subcutaneously to children with chronic renal failure

Braun, A., Ding, R., Seidel, C., Fies, T., Kurtz, Armin and Schärer, K. (1993) Pharmacokinetics of recombinant human erythropoietin applied subcutaneously to children with chronic renal failure. Pediatric nephrology 7 (1), pp. 61-64.

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Date of publication of this fulltext: 11 Dec 2012 08:56

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Abstract

The single-dose pharmacokinetics of recombinant human erythropoietin (rHuEPO) given SC was investigated in 20 patients aged 7-20 years at different stages of chronic renal failure. In a pilot study we confirmed the lower bioavailability of the drug in 2 children when given SC compared with the IV route (24% and 43%, respectively). Following administration of 4,000 units/m2, rHuEPO SC effective ...

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Item type:Article
Date:1993
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
8439481PubMed ID
Classification:
NotationType
AdolescentMESH
AdultMESH
ChildMESH
Erythropoietin/therapeutic useMESH
FemaleMESH
HumansMESH
Injections, IntravenousMESH
Injections, SubcutaneousMESH
Kidney Failure, Chronic/metabolismMESH
MaleMESH
Recombinant Proteins/therapeutic useMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26940
Owner only: item control page

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