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Increased plasma viscosity as a reason for inappropriate erythropoietin formation

Singh, A., Eckardt, Kai-Uwe, Zimmermann, A., Götz, Karlheinz, Hamann, M., Ratcliffe, P. J., Kurtz, Armin and Reinhart, W. H. (1993) Increased plasma viscosity as a reason for inappropriate erythropoietin formation. The Journal of clinical investigation 91 (1), pp. 251-256.

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Abstract

The aim of this study was to examine whether altered plasma viscosity could contribute to the inappropriately low production rate of erythropoietin (EPO) observed in patients suffering from hypergammaglobulinemias associated with multiple myeloma or Waldenström's disease. We found that the EPO formation in response to anemia in these patients was inversely related to plasma viscosity. A similar ...

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Item type:Article
Date:1993
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
8423222PubMed ID
10.1172/JCI116178DOI
Classification:
NotationType
AdultMESH
AgedMESH
AnimalsMESH
Blood PressureMESH
Blood ViscosityMESH
Erythropoietin/geneticsMESH
Exchange Transfusion, Whole BloodMESH
FemaleMESH
HematocritMESH
HumansMESH
Kidney/metabolismMESH
MaleMESH
Middle AgedMESH
Multiple Myeloma/bloodMESH
Oxygen/bloodMESH
RNA, Messenger/metabolismMESH
RatsMESH
Rats, Sprague-DawleyMESH
Rats, WistarMESH
Waldenstrom Macroglobulinemia/bloodMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26942
Owner only: item control page

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