Go to content
UR Home

Insulin-like growth factors decrease oxygen-regulated erythropoietin production by human hepatoma cells (Hep G2)

URN to cite this document:
urn:nbn:de:bvb:355-epub-269468
DOI to cite this document:
10.5283/epub.26946
Scholz, H. ; Baier, W. ; Ratcliffe, P. ; Eckardt, K. ; Zapf, J. ; Kurtz, Armin ; Bauer, C.
[img]
Preview
PDF
(1MB)
Date of publication of this fulltext: 04 Dec 2012 13:52



Abstract

We examined the effects of insulin-like growth factors (IGFs) and insulin on erythropoietin (EPO) production by human hepatoma cells (Hep G2). Compared with normoxia (20% O2), EPO production by Hep G2 cells during a 72-h incubation was stimulated fivefold by exposure to low oxygen tension (1% O2) and nearly threefold by exposure to cobalt chloride (100 microM). IGF-I caused a ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons