Go to content
UR Home

Insulin-like growth factors decrease oxygen-regulated erythropoietin production by human hepatoma cells (Hep G2)

Scholz, H., Baier, W., Ratcliffe, P., Eckardt, K., Zapf, J., Kurtz, Armin and Bauer, C. (1992) Insulin-like growth factors decrease oxygen-regulated erythropoietin production by human hepatoma cells (Hep G2). The American journal of physiology. Cell pyhsiology 263 (2 Pt 1), C474-C479.

[img]
Preview
PDF
Download (1MB)
Date of publication of this fulltext: 04 Dec 2012 13:52

at PubMed


Abstract

We examined the effects of insulin-like growth factors (IGFs) and insulin on erythropoietin (EPO) production by human hepatoma cells (Hep G2). Compared with normoxia (20% O2), EPO production by Hep G2 cells during a 72-h incubation was stimulated fivefold by exposure to low oxygen tension (1% O2) and nearly threefold by exposure to cobalt chloride (100 microM). IGF-I caused a ...

plus


Export bibliographical data



Item type:Article
Date:1992
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
1325119PubMed ID
Classification:
NotationType
AnimalsMESH
Culture MediaMESH
Dose-Response Relationship, DrugMESH
Erythropoietin/biosynthesisMESH
HumansMESH
Insulin/pharmacologyMESH
Insulin-Like Growth Factor I/pharmacologyMESH
Insulin-Like Growth Factor II/pharmacologyMESH
Liver Neoplasms/pathologyMESH
Liver Neoplasms, Experimental/pathologyMESH
Oxygen/pharmacologyMESH
Receptor, Insulin/metabolismMESH
Receptors, Cell Surface/metabolismMESH
Receptors, SomatomedinMESH
Somatomedins/pharmacologyMESH
Tumor Cells, CulturedMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26946
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons