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Calmodulin antagonists stimulate renin secretion and inhibit renin synthesis in vitro

Della Bruna, R., Pinet, F., Corvol, P. and Kurtz, Armin (1992) Calmodulin antagonists stimulate renin secretion and inhibit renin synthesis in vitro. The American journal of physiology 262 (3 Pt 2), F397-F402.

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Abstract

To find out whether calmodulin activity could be a common denominator for the cellular control of renin secretion and synthesis, we have examined the effects of calmodulin antagonists on the secretion and the synthesis of renin in primary cultures of mouse juxtaglomerular (JG) cells. We found that the calmodulin antagonists calmidazolium (CMDZ), N-(6-aminohexyl)-5-chloro-1-naphthalene-sulfonamide ...

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Item type:Article
Date:1992
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
1558157PubMed ID
Classification:
NotationType
AnimalsMESH
Calmodulin/antagonists & inhibitorsMESH
Cells, CulturedMESH
Cycloheximide/pharmacologyMESH
Imidazoles/pharmacologyMESH
Juxtaglomerular Apparatus/enzymologyMESH
KineticsMESH
MaleMESH
MiceMESH
Mice, Inbred C57BLMESH
Protein BiosynthesisMESH
Renin/secretionMESH
Sulfonamides/pharmacologyMESH
Sulfur RadioisotopesMESH
Trifluoperazine/pharmacologyMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26949
Owner only: item control page

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