Age-dependent expression of the erythropoietin gene in rat liver and kidneys

URN to cite this document:: urn:nbn:de:bvb:355-epub-269504

Eckardt, Kai-Uwe ; Ratcliffe, P. J. ; Tan, C. C. ; Bauer, Christian ; Kurtz, Armin

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Date of publication of this fulltext: 11 Dec 2012 13:08

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Abstract

Using RNAse protection, we have made quantitative measurements of erythropoietin (EPO) mRNA in liver and kidneys of developing rats (days 1-54), to determine the relative contribution of both organs to the total EPO mRNA, to monitor changes which occur with development, and to compare the hypoxia-induced accumulation of EPO mRNA with the changes in serum EPO concentrations. To determine whether ...