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Age-dependent expression of the erythropoietin gene in rat liver and kidneys

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Eckardt, Kai-Uwe ; Ratcliffe, P. J. ; Tan, C. C. ; Bauer, Christian ; Kurtz, Armin
Date of publication of this fulltext: 11 Dec 2012 13:08


Using RNAse protection, we have made quantitative measurements of erythropoietin (EPO) mRNA in liver and kidneys of developing rats (days 1-54), to determine the relative contribution of both organs to the total EPO mRNA, to monitor changes which occur with development, and to compare the hypoxia-induced accumulation of EPO mRNA with the changes in serum EPO concentrations. To determine whether ...


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