Insulin-like growth factor I: a modulator of erythropoiesis in uraemic patients?

URN to cite this document:: urn:nbn:de:bvb:355-epub-269534

Ureña, P. ; Bonnardeaux, A. ; Eckardt, Kai-Uwe ; Kurtz, Armin ; Drüeke, T. B.

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Date of publication of this fulltext: 13 Dec 2012 08:54

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Abstract

Anaemia is a feature almost invariably complicating chronic renal failure. Its pathophysiology is multifactorial but the most important cause is erythropoietin (Epo) deficiency. However, either no relation or even a weakly positive relation generally exists between serum immunoreactive (i) Epo and haematocrit values in uraemic anaemia, whereas in anaemias of non-renal origin the correlation is ...