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Endothelial cells modulate renin secretion from isolated mouse juxtaglomerular cells

Kurtz, Armin, Kaissling, B., Busse, Rr and Baier, W. (1991) Endothelial cells modulate renin secretion from isolated mouse juxtaglomerular cells. The Journal of clinical investigation 88 (4), pp. 1147-1154.

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Abstract

Utilizing cocultures of mouse renal juxtaglomerular cells with bovine microvascular endothelial cells, we have examined whether endothelial cells exert direct influence on renin secretion from renal juxtaglomerular cells. In the presence of endothelial cells both spontaneous and forskolin (10 microM) or isoproterenol (10 microM) stimulated renin release were markedly attenuated. The stimulatory ...

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Item type:Article
Date:1991
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
1717509PubMed ID
10.1172/JCI115415DOI
Classification:
NotationType
1-Methyl-3-isobutylxanthine/pharmacologyMESH
Adenosine Triphosphate/pharmacologyMESH
AnimalsMESH
Cells, CulturedMESH
Cyclic AMP/pharmacologyMESH
Endothelium, Vascular/physiologyMESH
Forskolin/pharmacologyMESH
Juxtaglomerular Apparatus/secretionMESH
MaleMESH
MiceMESH
Mice, Inbred C57BLMESH
Nitric Oxide/physiologyMESH
Renin/secretionMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26955
Owner only: item control page

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