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Determinants of renin secretion and renin synthesis in isolated mouse juxtaglomerular cells

Kurtz, Armin and della Bruna, R. D. (1991) Determinants of renin secretion and renin synthesis in isolated mouse juxtaglomerular cells. Kidney international. Supplement 32, S13-S15.

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Abstract

In this study we examined the effects of classic second messenger molecules on renin secretion and renin synthesis in primary cultures of mouse renal juxtaglomerular (JG) cells. Stimulation of cAMP formation by forskolin, inhibition of calmodulin by calmidazolium, and inhibition of Na+/H+ exchange by ethylisopropylamiloride enhanced renin secretion. Raising of intracellular cGMP by 8-bromo-cGMP ...

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Item type:Article
Date:1991
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
1652664PubMed ID
Classification:
NotationType
AnimalsMESH
Calmodulin/antagonists & inhibitorsMESH
Cyclic AMP/metabolismMESH
Forskolin/pharmacologyMESH
Imidazoles/pharmacologyMESH
Juxtaglomerular Apparatus/secretionMESH
MaleMESH
MiceMESH
Mice, Inbred C57BLMESH
Renin/secretionMESH
Second Messenger Systems/physiologyMESH
Signal Transduction/physiologyMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26961
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