Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-269717
DOI to cite this document:: 10.5283/epub.26971

Kurtz, Armin ; Skott, O. ; Chegini, S. ; Penner, R.

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Date of publication of this fulltext: 06 Dec 2012 13:47

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Abstract

In this study we have examined the role of voltage-gated calcium channels in the regulation of calcium in juxtaglomerular cells. Using a combination of patch-clamp and single-cell calcium measurement we obtained evidence neither for voltage-operated calcium currents nor for changes of the intracellular calcium concentration upon acute depolarizations of the cell membrane. Increases of the ...