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Molecular mechanisms of renin release

Kurtz, Armin ; Scholz, Holger ; della Bruna, R.



Abstract

Renin secretion from renal juxtaglomerular cells is controlled by the intrarenal blood pressure, sodium chloride load of the organism, sympathetic nerve activity, and a number of hormones. The mechanisms by which these parameters exert their effects are not well understood. However, it is reasonable to assume that they act via signal transduction systems, implying the role of second messenger ...

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