Calcitonin gene products and the kidney

URN to cite this document:: urn:nbn:de:bvb:355-epub-269780

Kurtz, Armin ; Muff, R. ; Fischer, J. A.

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Date of publication of this fulltext: 14 Dec 2012 09:51

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Abstract

Calcitonin gene-related peptide (CGRP) is localized in capsaicin-sensitive nerve fibres in the kidney and urogenital tract whereas calcitonin reaches the kidney through the general circulation. Systemic infusion of CGRP and perfusion of isolated rat kidney reduces vascular resistance, and increases renal blood flow and glomerular filtration. CGRP stimulates renin secretion in vivo and in vitro ...