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Angiotensin II induces oscillations of intracellular calcium and blocks anomalous inward rectifying potassium current in mouse renal juxtaglomerular cells

Kurtz, Armin and Penner, R. (1989) Angiotensin II induces oscillations of intracellular calcium and blocks anomalous inward rectifying potassium current in mouse renal juxtaglomerular cells. Proceedings of the National Academy of Sciences of the United States of America = PNAS 86 (9), pp. 3423-3427.

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Abstract

Simultaneous patch-clamp and fura-2 measurements were used to investigate the electrical properties and receptor-mediated changes of intracellular calcium in renal juxtaglomerular cells. Here we report the presence of voltage-activated inward and outward rectifying potassium currents and the inhibition of the anomalous inward rectifying potassium current by angiotensin II (ANG-II). This action of ...

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Item type:Article
Date:1989
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
2541447PubMed ID
Classification:
NotationType
Angiotensin II/pharmacologyMESH
AnimalsMESH
Calcium/metabolismMESH
Chloride ChannelsMESH
Chlorides/physiologyMESH
Cyclic AMP/pharmacologyMESH
Cyclic GMP/pharmacologyMESH
Electric ConductivityMESH
FemaleMESH
GTP-Binding Proteins/physiologyMESH
Guanosine 5'-O-(3-Thiotriphosphate)MESH
Guanosine Triphosphate/pharmacologyMESH
Juxtaglomerular Apparatus/physiologyMESH
KineticsMESH
Membrane Potentials/drug effectsMESH
Membrane Proteins/physiologyMESH
MiceMESH
Potassium Channels/physiologyMESH
Thionucleotides/pharmacologyMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26981
Owner only: item control page
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