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Stimulation of renin secretion by potassium-channel activation with cromakalim

Ferrier, C. P., Kurtz, Armin, Lehner, P., Shaw, S. G., Pusterla, C., Saxenhofer, H. and Weidmann, P. (1989) Stimulation of renin secretion by potassium-channel activation with cromakalim. European journal of clinical pharmacology 36 (5), pp. 443-447.

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Abstract

The cardiovascular and endocrine profile of cromakalim has been studied in 8 healthy men (age 25 +/- 2 years: means SEM) and its influence on renin release from cultured rat juxtaglomerular cells in vitro has also been examined. According to a double-blind, randomized sequence the subjects received placebo or cromakalim 1 mg as a single daily oral dose for 5 days. Compared to placebo, cromakalim ...

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Item type:Article
Date:1989
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
2666140PubMed ID
Classification:
NotationType
AdultMESH
Angiotensin II/pharmacologyMESH
Benzopyrans/pharmacologyMESH
Blood Pressure/drug effectsMESH
Cells, CulturedMESH
CromakalimMESH
Heart Rate/drug effectsMESH
HumansMESH
Juxtaglomerular Apparatus/metabolismMESH
MaleMESH
Potassium Channels/drug effectsMESH
Pyrroles/pharmacologyMESH
Renin/secretionMESH
Stimulation, ChemicalMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26986
Owner only: item control page

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