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Insulin-like growth factor I stimulates erythropoiesis in hypophysectomized rats

Kurtz, Armin, Zapf, J., Eckardt, Kai-Uwe, Clemons, G., Froesch, E. R. and Bauer, C. (1988) Insulin-like growth factor I stimulates erythropoiesis in hypophysectomized rats. Proceedings of the National Academy of Sciences of the United States of America : PNAS 85 (20), pp. 7825-7829.

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Abstract

Stimulation of erythropoiesis during growth is necessary to ensure proportionality between erythrocyte mass and body mass. However, the way by which erythrocyte formation is adapted to body growth is still unknown. Growth arrest in hypophysectomized rats is accompanied by decreased erythropoiesis. We have, therefore, examined whether insulin-like growth factor I (IGF-I), the mediator of growth ...

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Item type:Article
Date:1988
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
3174666PubMed ID
Classification:
NotationType
AnimalsMESH
Body Weight/drug effectsMESH
Erythrocyte CountMESH
Erythropoiesis/drug effectsMESH
Erythropoietin/bloodMESH
Growth Hormone/pharmacologyMESH
HematocritMESH
HypophysectomyMESH
Insulin-Like Growth Factor I/pharmacologyMESH
MaleMESH
RatsMESH
Recombinant Proteins/pharmacologyMESH
ReticulocytesMESH
Somatomedins/pharmacologyMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26993
Owner only: item control page

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