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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-269956
- DOI to cite this document:
- 10.5283/epub.26995
Alternative links to fulltext:Pubmed
Abstract
Stimulation of the renin-angiotensin system is a major side effect of the fungoid immunosuppressant cyclosporine A (CyA). The aim of this study was to find out whether or not this effect of CyA results from a direct interaction with renal juxtaglomerular (JG) cells, which are the site of renal renin synthesis and release. Using primary cell cultures from rat renal cortex containing more than 80% ...

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