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Cyclosporine A enhances renin secretion and production in isolated juxtaglomerular cells

Kurtz, Armin, Della Bruna, R. and Kühn, K. (1988) Cyclosporine A enhances renin secretion and production in isolated juxtaglomerular cells. Kidney international 33 (5), pp. 947-9453.

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Abstract

Stimulation of the renin-angiotensin system is a major side effect of the fungoid immunosuppressant cyclosporine A (CyA). The aim of this study was to find out whether or not this effect of CyA results from a direct interaction with renal juxtaglomerular (JG) cells, which are the site of renal renin synthesis and release. Using primary cell cultures from rat renal cortex containing more than 80% ...

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Item type:Article
Date:1988
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
3292818PubMed ID
Classification:
NotationType
AnimalsMESH
Cyclosporins/pharmacologyMESH
Juxtaglomerular Apparatus/secretionMESH
L-Lactate Dehydrogenase/metabolismMESH
RatsMESH
Renin/secretionMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26995
Owner only: item control page

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