Mechanism of NaCl transport-stimulated prostaglandin formation in MDCK cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-270018
DOI to cite this document:: 10.5283/epub.27001

Kurtz, Armin ; Pfeilschifter, J. ; Malmström, K. ; Woodson, R. D. ; Bauer, C.

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Date of publication of this fulltext: 05 Dec 2012 10:31

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Abstract

Recently we have found that stimulation of NaCl transport in high-resistance MDCK cells enhances their prostaglandin formation. In the present study, we investigated the mechanisms by which prostaglandin formation could be linked to the ion transport in these cells. We found that stimulation of transport caused a transient stimulation of prostaglandin formation lasting 5-10 min. The rise in ...