NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-270077
DOI to cite this document:: 10.5283/epub.27007

Kurtz, Armin ; Pfeilschifter, J. ; Brown, C. D. ; Bauer, C.

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Date of publication of this fulltext: 05 Dec 2012 10:30

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Abstract

Prostaglandins (PGs) can modulate a variety of renal functions, including Na+ and Cl- reabsorption. However, it is not known if a direct interdependence exists between PG synthesis and transport activity. The present study was done to find out whether or not the rate of NaCl transport has an influence on PG synthesis in renal tubular cells. For our studies we used cultures of so-called ...