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Role of phospholipase C and protein kinase C in vasoconstrictor-induced prostaglandin synthesis in cultured rat renal mesangial cells

Pfeilschifter, J., Kurtz, Armin and Bauer, Christian (1986) Role of phospholipase C and protein kinase C in vasoconstrictor-induced prostaglandin synthesis in cultured rat renal mesangial cells. The Biochemical journal 234 (1), pp. 125-130.

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Abstract

It was the aim of the present study to find out if a common mechanism exists by which the vasoconstrictive hormones angiotension II, noradrenaline and 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (AGEPC) increase prostaglandin E2 (PGE2) synthesis in cultures of rat renal mesangial cells. Angiotension II, noradrenaline and AGEPC stimulated PGE2 synthesis and uptake of 45Ca2+ in cultured ...

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Item type:Article
Date:1986
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
3458463PubMed ID
Classification:
NotationType
AnimalsMESH
Calcium/metabolismMESH
Cells, CulturedMESH
DinoprostoneMESH
Enzyme Activation/drug effectsMESH
Glomerular Mesangium/metabolismMESH
MaleMESH
Prostaglandins E/biosynthesisMESH
Protein Kinase C/metabolismMESH
RatsMESH
Rats, Inbred StrainsMESH
Type C Phospholipases/metabolismMESH
Vasoconstrictor Agents/pharmacologyMESH
Verapamil/pharmacologyMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:27009
Owner only: item control page

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