Erythropoietin production by fetal mouse liver cells in response to hypoxia and adenylate cyclase stimulation

URN to cite this document:: urn:nbn:de:bvb:355-epub-270105
DOI to cite this document:: 10.5283/epub.27010

Kurtz, Armin ; Jelkmann, W. ; Pfuhl, A. ; Malmström, K. ; Bauer, Christian

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Date of publication of this fulltext: 08 Jan 2013 08:09

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Abstract

This study was done to investigate aspects of control of extrarenal erythropoietin (Ep) production. To this end we studied the effects of three stimuli of renal Ep production in the adult, i.e. hypoxia, cobalt, and activation of adenylate cyclase on Ep generation by cultured fetal mouse liver cells. The fetal liver was taken as a model for extrarenal Ep production because this organ is considered ...