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Activation of phospholipase C and prostaglandin synthesis by [arginine]vasopressin in cultures
Pfeilschifter, J., Kurtz, Armin und Bauer, Christian (1984) Activation of phospholipase C and prostaglandin synthesis by [arginine]vasopressin in cultures. The Biochemical journal 223 (3), S. 855-859.Veröffentlichungsdatum dieses Volltextes: 08 Jan 2013 09:13
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DOI zum Zitieren dieses Dokuments: 10.5283/epub.27017
Zusammenfassung
[Arginine]vasopressin (AVP) stimulates maximal prostaglandin E2 production in cultured rat renal mesangial cells within 2 min. As early as 10s after addition of AVP (10(-6)M) a significant loss of radioactivity from phosphatidylinositol 4,5-bisphosphate but not from phosphatidylinositol 4-phosphate and phosphatidylinositol was observed in cells prelabelled with 32Pi. Cells labelled with ...
[Arginine]vasopressin (AVP) stimulates maximal prostaglandin E2 production in cultured rat renal mesangial cells within 2 min. As early as 10s after addition of AVP (10(-6)M) a significant loss of radioactivity from phosphatidylinositol 4,5-bisphosphate but not from phosphatidylinositol 4-phosphate and phosphatidylinositol was observed in cells prelabelled with 32Pi. Cells labelled with [14C]arachidonic acid showed an increase of label in 1,2-diacylglycerol after 15 s and in phosphatidic acid after 30 s upon stimulation with AVP. Pretreatment of the cells with indomethacin (10(-5)M) did not abolish the effect of AVP on the increased labelling of phosphatidic acid.
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| Dokumentenart | Artikel | ||||||||||||||||||||||||||||
| Titel eines Journals oder einer Zeitschrift | The Biochemical journal | ||||||||||||||||||||||||||||
| Verlag: | Portland Press | ||||||||||||||||||||||||||||
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| Band: | 223 | ||||||||||||||||||||||||||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 3 | ||||||||||||||||||||||||||||
| Seitenbereich: | S. 855-859 | ||||||||||||||||||||||||||||
| Datum | 1984 | ||||||||||||||||||||||||||||
| Institutionen | Biologie und Vorklinische Medizin > Institut für Physiologie > Prof. Dr. Armin Kurtz | ||||||||||||||||||||||||||||
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| Klassifikation |
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| Dewey-Dezimal-Klassifikation | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin | ||||||||||||||||||||||||||||
| Status | Veröffentlicht | ||||||||||||||||||||||||||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||||||||||||||||||||||||||
| An der Universität Regensburg entstanden | Unbekannt / Keine Angabe | ||||||||||||||||||||||||||||
| URN der UB Regensburg | urn:nbn:de:bvb:355-epub-270173 | ||||||||||||||||||||||||||||
| Dokumenten-ID | 27017 |
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