Extraction of erythropoietin from isolated renal glomeruli of hypoxic rats

URN to cite this document:: urn:nbn:de:bvb:355-epub-270189
DOI to cite this document:: 10.5283/epub.27018

Jelkmann, W. ; Kurtz, Armin ; Bauer, Christian

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Date of publication of this fulltext: 08 Jan 2013 14:20

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Abstract

We investigated whether erythropoietin (Ep) can be extracted from renal glomeruli of hypoxic rats. Hypoxia was induced in a hypobaric chamber at 0.42 atmospheres for usually 6 h. Glomeruli were isolated with a sieving technique from kidneys that were flushed free of blood. Ep activities in glomeruli homogenates were determined in the fetal mouse liver cell assay and in the hypoxia exposed mouse ...