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Renal mesangial cell cultures as a model for study of erythropoietin production

Kurtz, Armin, Jelkmann, W., Sinowatz, F. and Bauer, Christian (1983) Renal mesangial cell cultures as a model for study of erythropoietin production. Proceedings of the National Academy of Sciences of the United States of America : PNAS 80 (13), pp. 4008-4011.

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Abstract

Mesangial cells derived from isolated glomeruli of rat kidney were grown as homogeneous cell lines in culture. They released, into the culture medium, erythropoietin that had free terminal galactosyl residues and was therefore not active in vivo. The production of erythropoietin by these cells was significantly enhanced by either lowering the PO2 in the incubation atmosphere or by adding cobalt ...

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Item type:Article
Date:1983
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Identification Number:
ValueType
6346323PubMed ID
Classification:
NotationType
AnimalsMESH
Cells, CulturedMESH
Erythropoietin/biosynthesisMESH
Kidney Glomerulus/ultrastructureMESH
Macrophage-1 AntigenMESH
Microscopy, ElectronMESH
OxygenMESH
Partial PressureMESH
RatsMESH
Receptors, Complement/analysisMESH
Receptors, Fc/analysisMESH
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:27019
Owner only: item control page

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