A new candidate for the regulation of erythropoiesis. Insulin-like growth factor I

URN to cite this document:: urn:nbn:de:bvb:355-epub-270224
DOI to cite this document:: 10.5283/epub.27022

Kurtz, Armin ; Jelkmann, W. ; Bauer, Christian

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Date of publication of this fulltext: 06 Dec 2012 13:45

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Abstract

The effect of pure human insulin-like growth factor I (IGF I) on the colony formation of late stage erythroid precursor cells (CFU-e) from fetal mouse liver and adult bone marrow was studied in a serum-free culture system. We found that IGF I in physiological concentrations stimulated erythroid colony formation. The combined effect of IGF I and erythropoietin was smaller than the sum of their ...