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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-271332
- DOI to cite this document:
- 10.5283/epub.27133
Alternative links to fulltext:DOI
Abstract
The electrophilic nature of chalcones (1,3-diphenylprop-2-en-1-ones) and many other α,β-unsaturated carbonyl compounds is crucial for their biological activity, which is often based on thiol-mediated regulation processes. To better predict their biological activity a simple screening assay for the assessment of the second-order rate constants (k2) in thia-Michael additions was developed. Hence, a ...

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