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Wege zur Th17-Zelldifferenzierung in vitro

Hiller, Julia Miriam (2013) Wege zur Th17-Zelldifferenzierung in vitro. PhD, Universität Regensburg.

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Date of publication of this fulltext: 11 Jan 2013 09:49

Abstract (German)

Th17-Zellen sind seit ihrer Entdeckung als Subpopulation der CD4-positiven T-Zellen Gegenstand intensiver Forschung. Neben ihrer Beteiligung an Autoimmunkrankheiten wird ihnen auch eine wichtige Aufgabe bei der Abwehr extrazellulärer Pathogene zugeschrieben und eine Vermittlerrolle zwischen angeborenem und adaptivem Immunsystem. Wichtige Wachstumsfaktoren für ihre Proliferation in vitro sind TGFß ...

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Translation of the abstract (English)

Since their discovery as an essential subset of CD4-positive T-cells, Th17-T-Cells have been the focus of intensive research. Along with their involvement in autoimmune diseases, they seem to fulfill an important response in the defense of extracellular pathogens and are obviously also a major link between innate and adaptive immunity. For differentiation in vitro, IL-6 and TGFß are necessary ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:11 January 2013
Referee:Prof .Dr. Daniela N. Männel
Date of exam:16 November 2012
Institutions:Medicine > Lehrstuhl für Immunologie
Interdisciplinary Subject Network:Not selected
Keywords:Th17-Zellen, IL-7, IL-2
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:27138
Owner only: item control page

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