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Effekte von Elicitin auf Wachstum, Proliferation und Signaltransduktion von Tumorzellen in vitro

Mross, Felix (2012) Effekte von Elicitin auf Wachstum, Proliferation und Signaltransduktion von Tumorzellen in vitro. PhD, Universität Regensburg.

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Date of publication of this fulltext: 19 Dec 2012 07:40

Abstract (German)

Ungeachtet neuester Errungenschaften auf dem Gebiet der medizinischen Forschung steigen die globalen krebsbedingten Todesfälle stetig an und es gilt, kontinuierlich neue Medikamente zu entdecken und zu entwickeln, die eine Antitumortherapie effizienter, nebenwirkungsärmer oder überhaupt erst möglich machen. Diese pharmakologische Weiterentwicklung konnte im Laufe der Geschichte bereits vielfach ...

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Translation of the abstract (English)

As the incidence of malignant diseases is rising constantly, there is always need for new substances, making antiproliferative therapy more effective or possible in the first place. Many chemotherapeutic agents which are known at the moment are produced from plants and fungi. Being produced by the fungal-like organism Phythophtora, Elicitins have been shown to elicit strong cytotoxic effects in ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:19 December 2012
Referee:Prof. Dr. Edward K. Geissler and Prof. Dr. Wolfgang Oßwald
Date of exam:17 December 2012
Institutions:Medicine > Lehrstuhl für Chirurgie
Keywords:Cancer, Elicitin, Phythophtora, MAPK, H2O2, Microtubule destruction, Warburg effect
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:27146
Owner only: item control page

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