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Linear poly(ethylene imine)-poly(ethylene glycol) copolymers for nucleic acid delivery - Synthesis and characterization

Bauhuber, Sonja (2013) Linear poly(ethylene imine)-poly(ethylene glycol) copolymers for nucleic acid delivery - Synthesis and characterization. PhD, Universität Regensburg.

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Date of publication of this fulltext: 02 Dec 2013 15:26

Abstract (English)

In the last years the delivery of nucleic acids has emerged as a promising strategy for the modulation of gene expression. It has been shown to be a useful tool for both, the insertion of therapeutic genes via DNA and the inhibition of harmful or non-functional proteins by the application of therapeutic RNA [1, 2]. These approaches proofed to be helpful for the therapy of severe acquired or ...

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Translation of the abstract (English)

In den letzten Jahren hat sich der zielgerichtete Transport von Nukleinsäuren als vielversprechende Strategie für die Modulation der Genexpression erwiesen. Dieser Transport ist ein nützliches Werkzeug sowohl für das Einfügen therapeutischer Gene mit Hilfe von pDNA also auch für die Inhibition schädlicher oder nichtfunktionsfähiger Proteine durch die Verwendung therapeutischer RNA [1,2]. Diese ...

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Export bibliographical data



Item type:Thesis of the University of Regensburg (PhD)
Date:2 December 2013
Referee:Prof. Dr. Achim Göpferich
Date of exam:30 November 2012
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Keywords:Gene delivery, PEI, PEG, disulfide
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:27171
Owner only: item control page

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