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Haspin-Proteine der Hefe sind negative Regulatoren der Zellpolarität

URN to cite this document:
urn:nbn:de:bvb:355-epub-273171
Swoboda, Britta
Date of publication of this fulltext: 16 Dec 2013 16:29


Abstract (German)

Haspine sind Serin/Threonin-Kinasen, die aufgrund ihrer abweichenden Struktur eine distinkte Subgruppe von eukaryotischen Proteinkinasen bilden. Der Name (haploid germ cell specific nuclear protein kinase) reflektiert ihre Entdeckung in testikularen Maus-Gameten, wobei inzwischen bekannt ist, dass sie ubiquitär in proliferierenden Zellen aller bislang untersuchten Organismen exprimiert werden. In ...

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Translation of the abstract (English)

Haspins are serin/threonine kinases which form, due to their different structure, a distinct subgroup of eukaryotic protein kinases. The name haploid germ cell specific nuclear protein kinase (Haspin) reflects their discovery in testicular mice germ cells, however it is known, to date, that they are ubiquitaryly expressed in all probed organisms. In mammals, plants, S. pombe and X. laevis, ...

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