Go to content
UR Home

The impact of intragenic CpG content on epigenetic control of transgene expression in mammalian cells

URN to cite this document:
urn:nbn:de:bvb:355-epub-274107
Krinner, Simone
Date of publication of this fulltext: 24 Jan 2014 12:30


Abstract (English)

The improvement of gene therapy applications and efficient production of recombinant therapeutics in mammalian cells is a growing field of interest in medical and pharmaceutical research. Plasmid-DNA (pDNA)-based vector systems offer an innovative gene transfer strategy due to their high stability, cost efficient production and their excellent safety profile. Despite these advantages, the ...

plus

Translation of the abstract (German)

Die effiziente Produktion rekombinanter Therapeutika in Säugerzellen und Verbesserung gentherapeutischer Verfahren sind bedeutende und expandierende Felder in der medizinischen und pharmazeutischen Forschung. Plasmid-DNA (pDNA)-basierte Vektorsysteme stellen aufgrund ihrer Stabilität, der kostengünstigen Produktion sowie ihres hervorragenden Sicherheitsprofils ein innovatives Gentransfer-System ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons