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Hypertrophie chondrogen differenzierender mesenchymaler Stammzellen im dreidimensionalen System

Teegen, Eva Maria (2013) Hypertrophie chondrogen differenzierender mesenchymaler Stammzellen im dreidimensionalen System. PhD, Universität Regensburg.

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Date of publication of this fulltext: 13 Mar 2013 15:57

Abstract (German)

Tissue Engineering bietet Therapieoptionen wie die autologe Chondrozytentrans-plantation, verknüpft mit dem Nachteil, dass bei der Zellentnahme gesundes Gewebe verletzt wird (Donormorbidität). Einfacher lassen sich humane mesenchymalen Stammzellen aus dem Beckenkamm gewinnen, in vitro proliferieren und zu reifen Chondrozyten differenzieren (11, 50, 80, 89, 93, 102, 112). In vitro aber ...

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Translation of the abstract (English)

Tissue engineering offers therapy concepts like the autologous chondrocyte transplantation going along with the drawback of injured healthy tissue (donormorbidity). Human mesenchymal stem cells (MSC) are easily extracted from the iliac crest, in vitro proliferated and differentiated to mature chondrocytes (11, 50, 80, 89, 93, 102, 112). But predifferentiated MSCs expressed hypertrophic markers in ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:13 March 2013
Referee:Prof. Dr. Peter Angele
Date of exam:19 February 2013
Institutions:Medicine > Lehrstuhl für Unfallchirurgie
Keywords:mesenchymale Stammzellen, Tissue engineering, Knorpel, Arthrose, Hypertrophie, PTHrP
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:27826
Owner only: item control page

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