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Novel liquid application systems for poorly soluble drugs

Luschmann, Christoph Roman (2015) Novel liquid application systems for poorly soluble drugs. PhD, Universität Regensburg.

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Date of publication of this fulltext: 19 Jan 2015 14:15

Abstract (English)

This thesis was focused on the development of efficient novel liquid formulations for poorly water soluble drugs for the treatment of inflammatory ophthalmic diseases. With Restasis® there is currently only one drug product approved by the FDA, in the US only, for the treatment of dry eye syndrome. It still suffers from low bioavailability, bad biocompatibility and thus a low patient compliance, ...

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Translation of the abstract (German)

In der vorliegenden Arbeit wurden neuartige, flüssige Formulierungen für schwer wasserlösliche Arzneistoffe zur Behandlung entzündlicher Erkrankungen des vorderen Auges entwickelt. Aktuell ist mit dem Präparat Restasis® nur rein einziges Fertigarzneimittel zur Behandlung der Keratokonjunctivitis sicca von der FDA zugelassen und dieses auch nur für den US amerikanischen Raum. Leider bringt auch ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:19 January 2015
Referee:Prof. Dr. Achim Göpferich
Date of exam:15 March 2013
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Keywords:cyclosporin A, budesonide, in-situ nanosuspension, micellar solution, bioavailability, biocompatibility, liquid
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:27948
Owner only: item control page

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