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Pharmacokinetics of moxifloxacin in plasma and tissue of morbidly obese patients

Kees, Martin G. ; Weber, Susanne ; Kees, Frieder K. ; Horbach, Thomas



Abstract

Objectives: To assess the pharmacokinetics of moxifloxacin in morbidly obese patients. Methods: Twelve morbidly obese patients (2 male/10 female, age 25–61 years, weight 98–166 kg, body mass index 43.0–58.2 kg/m2) scheduled for gastric bypass surgery were treated with 400 mg of moxifloxacin orally once daily for 3 days and with 400 mg of moxifloxacin intravenously on day 4 (day of surgery). ...

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