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FAT1 expression and function in chronic liver disease and hepatocellular carcinoma

Valletta, Daniela (2014) FAT1 expression and function in chronic liver disease and hepatocellular carcinoma. PhD, Universität Regensburg.

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Date of publication of this fulltext: 13 May 2014 17:32

Abstract (English)

FAT1 is a member of the atypical cadherin FAT subfamily. The first identified member of this family was Drosophila Fat which has been regarded as a tumor suppressor because of its implication in tissue growth. In vertebrates FAT subfamily consists of 4 members, FAT1, -2, -3 and FAT-J (or FAT4). Only FAT1 has so far been studied more intensively. FAT1 is expressed in a wide range of tissues and a ...

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Translation of the abstract (German)

FAT1 ist ein Mitglied der atypischen Cadherin-Subfamilie FAT. Das erste identifizierte Mitglied dieser Familie war Drosophila Fat. Dieses wurde aufgrund seiner Funktion im Gewebewachstum als Tumorsuppressor angesehen. In Vertebraten besteht die FAT Subfamilie aus 4 Mitgliedern: FAT1, -2, -3 und FAT-J (FAT4), von denen nur FAT1 genauer erforscht wurde. FAT1 wird in vielen Geweben exprimiert. Ein ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:13 May 2014
Referee:Prof. Dr. Claus Hellerbrand
Date of exam:30 April 2013
Institutions:Medicine > Lehrstuhl für Innere Medizin I
Keywords:FAT1, liver disease, HCC
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:28202
Owner only: item control page

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