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Synthesis of substituted hydantoins in low melting mixtures

URN to cite this document:
urn:nbn:de:bvb:355-epub-282090
DOI to cite this document:
10.5283/epub.28209
Gore, Sangram ; Chinthapally, Kiran ; Baskaran, Sundarababu ; König, Burkhard
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Date of publication of this fulltext: 16 May 2013 06:23


Abstract

A novel domino synthesis of 1,3,5-trisubstituted hydantoin derivatives has been developed in low melting l-(+)-tartaric acid-DMU melt mixtures. The functionalized hydantoins are obtained in good yields from β,γ-unsaturated ketoacids and urea under environmentally benign and simple reaction conditions.


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