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Datenbank-gestützte molekularbiologische Analyse melanomrelevanter Gene

Hetterich, Sonja (2014) Datenbank-gestützte molekularbiologische Analyse melanomrelevanter Gene. PhD, Universität Regensburg.

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Date of publication of this fulltext: 01 Aug 2014 14:53

Abstract (German)

Das maligne Melanom, das von den Melanozyten der Haut ausgeht, zählt zu den bösar-tigsten Tumorerkrankungen des Menschen. Aufgrund seiner Eigenschaft frühzeitig zu metastasieren, ist es durch eine oft schlechte Prognose und einen häufig letalen Verlauf gekennzeichnet. Häufige Ursachen für die Entartung der Melanozyten sind Mutationen oder Expressionsänderungen von Genen dieser Zellen. In den ...

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Translation of the abstract (English)

Malignant melanoma, which derives from the melanocytes of the skin, belongs to the most malignant human neoplasias. Because of its ability to metastasize at an early stage, it is often characterized by a poor prognosis and a lethal progress. Common causes for the transformation of melanocytes are mutations or changes in gene expression of these cells. During the last years, progress was made ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:August 2014
Referee:Prof. Dr. Anja-Katrin Bosserhoff
Date of exam:30 July 2013
Institutions:Medicine > Lehrstuhl für Pathologie
Keywords:malignes Melanom, GEO Profiles, Microarray, KCNN2, SHFM1, PLXNA1, FOXD1
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:28629
Owner only: item control page

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