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GPER-1 acts as a tumor suppressor in ovarian cancer

URN to cite this document:
urn:nbn:de:bvb:355-epub-287868
Ignatov, Tanja ; Modl, Saskia ; Thulig, Maike ; Weißenborn, Christine ; Treeck, Oliver ; Ortmann, Olaf ; Zenclussen, Ac ; Costa, Serban Dan ; Kalinski, Thomas ; Ignatov, Atanas
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Date of publication of this fulltext: 03 Sep 2013 12:55


Abstract

Background: It is known that the new membrane-bound estrogen receptor GPER-1 acts suppressive in breast cancer cells and its expression decreases during disease progression. This study was conducted to evaluate the GPER-1 expression in ovarian cancer and its correlation with progression. Its function was tested in vitro in ovarian cancer cells. PATIENTS AND METHODS: GPER-1 expression was analyzed ...

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