GPER-1 acts as a tumor suppressor in ovarian cancer

URN to cite this document:: urn:nbn:de:bvb:355-epub-287868
DOI to cite this document:: 10.5283/epub.28786

Ignatov, Tanja ; Modl, Saskia ; Thulig, Maike ; Weißenborn, Christine ; Treeck, Oliver ; Ortmann, Olaf ; Zenclussen, Ac

; Costa, Serban-Dan ; Kalinski, Thomas ; Ignatov, Atanas

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Date of publication of this fulltext: 03 Sep 2013 12:55

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Abstract

Background: It is known that the new membrane-bound estrogen receptor GPER-1 acts suppressive in breast cancer cells and its expression decreases during disease progression. This study was conducted to evaluate the GPER-1 expression in ovarian cancer and its correlation with progression. Its function was tested in vitro in ovarian cancer cells. Patients and methods: GPER-1 expression was analyzed ...