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Membrane trafficking of death receptors: implications on signalling

Schneider-Brachert, Wulf, Heigl, Ulrike and Ehrenschwender, Martin (2013) Membrane trafficking of death receptors: implications on signalling. International journal of molecular sciences 14 (7), pp. 14475-14503.

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Date of publication of this fulltext: 11 Sep 2013 08:42

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Abstract

Death receptors were initially recognised as potent inducers of apoptotic cell death and soon ambitious attempts were made to exploit selective ignition of controlled cellular suicide as therapeutic strategy in malignant diseases. However, the complexity of death receptor signalling has increased substantially during recent years. Beyond activation of the apoptotic cascade, involvement in a ...

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Item type:Article
Date:2013
Institutions:Medicine > Lehrstuhl für Medizinische Mikrobiologie und Hygiene
Projects:Open Access Publizieren (DFG)
Identification Number:
ValueType
23852022PubMed ID
10.3390/ijms140714475DOI
Keywords:death receptor; apoptosis; endocytosis; membrane trafficking; receptor internalisation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:28828
Owner only: item control page

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