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Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial

Wick, Wolfgang, Platten, Michael, Meisner, Christoph, Felsberg, Jörg, Tabatabai, Ghazaleh, Simon, Matthias, Nikkhah, Guido, Papsdorf, Kirsten, Steinbach, Joachim P., Sabel, Michael, Combs, Stephanie E., Vesper, Jan, Braun, Christian, Meixensberger, Jürgen, Ketter, Ralf, Mayer-Steinacker, Regine, Reifenberger, Guido and Weller, Michael (2012) Temozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trial. The lancet oncology 13 (7), pp. 707-715.

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Merck Sharp & Dohme.


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Item type:Article
Date:2012
Additional Information (public):NOA-08 Study Group of Neuro-oncology Working Group (NOA) of German Cancer Society
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
22846836PubMed ID
10.1016/S1470-2045(12)70164-XDOI
Classification:
NotationType
AgedMESH
Aged, 80 and overMESH
Antineoplastic Agents, Alkylating/therapeutic useMESH
Astrocytoma/radiotherapyMESH
Brain Neoplasms/radiotherapyMESH
DNA MethylationMESH
DNA Modification Methylases/geneticsMESH
DNA Repair Enzymes/geneticsMESH
Dacarbazine/therapeutic useMESH
Disease-Free SurvivalMESH
FemaleMESH
HumansMESH
Isocitrate Dehydrogenase/geneticsMESH
MaleMESH
Promoter Regions, GeneticMESH
Tumor Suppressor Proteins/geneticsMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29174
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