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Neuronatin in a subset of glioblastoma multiforme tumor progenitor cells is associated with increased cell proliferation and shorter patient survival

Xu, David S., Yang, Chunzhang, Proescholdt, Martin A., Bründl, Elisabeth, Brawanski, Alexander, Fang, Xueping, Lee, Cheng S., Weil, Robert J., Zhuang, Zhengping and Lonser, Russell R. (2012) Neuronatin in a subset of glioblastoma multiforme tumor progenitor cells is associated with increased cell proliferation and shorter patient survival. PloS one 7 (5), e37811.

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Abstract

Glioblastoma multiforme is the most common and malignant primary brain tumor. Recent evidence indicates that a subset of glioblastoma tumor cells have a stem cell like phenotype that underlies chemotherapy resistance and tumor recurrence. We utilized a new "multidimensional" capillary isoelectric focusing nano-reversed-phase liquid chromatography platform with tandem mass spectrometry to compare ...

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Item type:Article
Date:2012
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
19218280PubMed ID
10.1371/journal.pone.0037811DOI
Classification:
NotationType
Biological Markers/metabolismMESH
Cell ProliferationMESH
Chromatography, LiquidMESH
Glioblastoma/metabolismMESH
HumansMESH
Isoelectric FocusingMESH
Kaplan-Meier EstimateMESH
Membrane Proteins/metabolismMESH
Neoplastic Stem Cells/metabolismMESH
Nerve Tissue Proteins/metabolismMESH
Protein Isoforms/metabolismMESH
Proteomics/methodsMESH
Tandem Mass SpectrometryMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29175
Owner only: item control page

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