Neuronatin in a subset of glioblastoma multiforme tumor progenitor cells is associated with increased cell proliferation and shorter patient survival

URN to cite this document:: urn:nbn:de:bvb:355-epub-291750
DOI to cite this document:: 10.5283/epub.29175

Xu, David S. ; Yang, Chunzhang ; Proescholdt, Martin A. ; Bründl, Elisabeth ; Brawanski, Alexander ; Fang, Xueping ; Lee, Cheng S. ; Weil, Robert J. ; Zhuang, Zhengping ; Lonser, Russell R.

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Date of publication of this fulltext: 09 Dec 2013 11:04

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Abstract

Glioblastoma multiforme is the most common and malignant primary brain tumor. Recent evidence indicates that a subset of glioblastoma tumor cells have a stem cell like phenotype that underlies chemotherapy resistance and tumor recurrence. We utilized a new "multidimensional" capillary isoelectric focusing nano-reversed-phase liquid chromatography platform with tandem mass spectrometry to compare ...