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Lindemann, Carina ; Hackmann, Oliver ; Delic, Sabit ; Schmidt, Natalie ; Reifenberger, Guido ; Riemenschneider, Markus J.

SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gliomas and promotes glioma cell invasion through STAT3 and FAK activation

Lindemann, Carina, Hackmann, Oliver, Delic, Sabit, Schmidt, Natalie, Reifenberger, Guido and Riemenschneider, Markus J. (2011) SOCS3 promoter methylation is mutually exclusive to EGFR amplification in gliomas and promotes glioma cell invasion through STAT3 and FAK activation. Acta neuropathologica 122 (2), pp. 241-251.

Date of publication of this fulltext: 11 Dec 2013 12:53
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Item typeArticle
Journal or Publication TitleActa neuropathologica
Publisher:SPRINGER
Place of Publication:NEW YORK
Volume:122
Number of Issue or Book Chapter:2
Page Range:pp. 241-251
Date2011
InstitutionsMedicine > Abteilung für Neuropathologie
Identification Number
ValueType
21590492PubMed ID
10.1007/s00401-011-0832-0DOI
Classification
NotationType
Blotting, WesternMESH
Brain Neoplasms/pathologyMESH
DNA Methylation/geneticsMESH
DNA Mutational AnalysisMESH
Enzyme Activation/physiologyMESH
Focal Adhesion Kinase 1/metabolismMESH
Gene AmplificationMESH
Genes, erbB-1MESH
Glioma/pathologyMESH
HumansMESH
ImmunohistochemistryMESH
Neoplasm Invasiveness/geneticsMESH
Promoter Regions, Genetic/geneticsMESH
Reverse Transcriptase Polymerase Chain ReactionMESH
STAT3 Transcription Factor/metabolismMESH
Signal Transduction/geneticsMESH
Suppressor of Cytokine Signaling Proteins/metabolismMESH
KeywordsTRANSCRIPTIONAL DOWN-REGULATION; HEPATOCELLULAR-CARCINOMA; GLIOBLASTOMA-MULTIFORME; GROWTH; HYPERMETHYLATION; GENE; CANCER; EXPRESSION; SUPPRESSORS; PATHWAY; Brain tumor; Glioblastoma; Astrocytoma; JAK; MAPK; AKT
Dewey Decimal Classification600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgUnknown
Item ID29183

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