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Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19q

Grzendowski, Michael, Wolter, Marietta, Riemenschneider, Markus J., Knobbe, Christiane B., Schlegel, Uwe, Meyer, Helmut E., Reifenberger, Guido and Stühler, Kai (2010) Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19q. Neuro-oncology 12 (3), pp. 243-256.

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Abstract

Combined deletion of chromosomal arms 1p and 19q is an independent prognostic marker in patients with oligodendroglial brain tumors, including oligodendrogliomas and oligoastrocytomas. However, the relevant genes in these chromosome arms and the molecular mechanisms underlying the prognostic significance of 1p/19q deletion are yet unknown. We used two-dimensional difference gel electrophoresis ...

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Item type:Article
Date:2010
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
17311001PubMed ID
10.1093/neuonc/nop025DOI
Classification:
NotationType
Blotting, WesternMESH
Brain Neoplasms/geneticsMESH
Chromosomes, Human, Pair 1/geneticsMESH
Chromosomes, Human, Pair 19/geneticsMESH
DNA Methylation/geneticsMESH
Electrophoresis, Gel, Two-DimensionalMESH
Gene ExpressionMESH
Gene Expression ProfilingMESH
Gene Expression Regulation, NeoplasticMESH
Glioma/geneticsMESH
HumansMESH
Image Processing, Computer-AssistedMESH
ImmunohistochemistryMESH
Loss of Heterozygosity/geneticsMESH
PrognosisMESH
Protein Array AnalysisMESH
ProteomicsMESH
Reverse Transcriptase Polymerase Chain ReactionMESH
Spectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29211
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