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Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma

Eigentler, Thomas K. ; Figl, Adina ; Krex, Dietmar ; Mohr, Peter ; Mauch, Cornelia ; Rass, Knut ; Bostroem, Azize ; Heese, Oliver ; Koelbl, Oliver ; Garbe, Claus ; Schadendorf, Dirk


The overall survival of patients with BM-MM primarily depends on the number of metastases and pretreatment level of LDH. In the case of a single brain metastasis, stereotactic radiotherapy or neurosurgical metastasectomy is by far the most important factor for improving survival.

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