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Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma

Eigentler, Thomas K. ; Figl, Adina ; Krex, Dietmar ; Mohr, Peter ; Mauch, Cornelia ; Rass, Knut ; Bostroem, Azize ; Heese, Oliver ; Koelbl, Oliver ; Garbe, Claus ; Schadendorf, Dirk



Abstract

BACKGROUND: This multicenter study aimed to identify prognostic factors in patients with brain metastases from malignant melanoma (BM-MM). METHODS: In a retrospective survey in 9 cancer centers of the German Cancer Society, 692 patients were identified with BM-MM during the period 1986 through 2007. Overall survival was analyzed using a Kaplan-Meier estimator and compared with log-rank analysis. ...

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