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Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma

Eigentler, Thomas K., Figl, Adina, Krex, Dietmar, Mohr, Peter, Mauch, Cornelia, Rass, Knut, Bostroem, Azize, Heese, Oliver, Koelbl, Oliver, Garbe, Claus and Schadendorf, Dirk (2011) Number of metastases, serum lactate dehydrogenase level, and type of treatment are prognostic factors in patients with brain metastases of malignant melanoma. Cancer 117 (8), pp. 1697-1703.

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Abstract

The overall survival of patients with BM-MM primarily depends on the number of metastases and pretreatment level of LDH. In the case of a single brain metastasis, stereotactic radiotherapy or neurosurgical metastasectomy is by far the most important factor for improving survival.


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Item type:Article
Date:2011
Additional Information (public):Dermatologic Cooperative Oncology Group and the National Interdisciplinary Working Group on Melanoma
Institutions:Medicine > Zentren des Universitätsklinikums Regensburg > Zentrum für Hirntumore (ZHT)
Identification Number:
ValueType
21472703PubMed ID
10.1002/cncr.25631DOI
Classification:
NotationType
AdolescentMESH
AdultMESH
AgedMESH
Aged, 80 and overMESH
Brain Neoplasms/therapyMESH
ChildMESH
FemaleMESH
HumansMESH
L-Lactate Dehydrogenase/bloodMESH
Melanoma/therapyMESH
Middle AgedMESH
PrognosisMESH
Skin Neoplasms/pathologyMESH
Survival AnalysisMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:29215
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